Stalevo 125mg+31.25mg+200mg Tablet | 30Pcs | Price
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Home Medicines Parkinson's Syndrome Stalevo (125mg+31.25mg+200mg) Tablet 30Pcs
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Stalevo (125mg+31.25mg+200mg) Tablet 30Pcs

Generic: Levodopa + Carbidopa + Entacapone

Type: Tablet

Pack Size: 30 Pcs

Stalevo is a combination of Levodopa which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa manages the breakdown of Levodopa by allowing it to enter the brain for increased dopamine levels and Entacapone maintains the level of levodopa in the blood. All these collective actions provide greater relief from the symptoms of Parkinson’s disease.


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Discount Price: ৳ 3052.8
MRP: ৳ 3180 4% Off

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✅ Description:

  • Levodopa + Carbidopa + Entacapone is a prescription medicine used in the treatment of Parkinson's disease.
  • This medicine helps to reduce excessive shaking by slowing down the body movements. It works by increasing the amount of chemical messenger that is needed to control abnormal movements.
  • Levodopa + Carbidopa + Entacapone Tablet is taken with or without food, but better to avoid high-protein meals and dairy products. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body.
  • Take this medicine in the dose and duration advised by your doctor and if you have missed a dose, take it as soon as you remember.
  • You should never skip any doses and try to finish the full course of treatment even if you feel better.
  • Levodopa + Carbidopa + Entacapone mustn't be stopped suddenly without talking to the doctor as it can result in harmful effects.

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✔️ Uses of Stalevo 125mg+31.25mg+200mg Tablet
  • Manage Parkinson’s disease
✔️ How does Stalevo 125mg+31.25mg+200mg Tablet work?

Stalevo 125mg+31.25mg+200mg Tablet combines three active ingredients:

  • Levodopa: Converts to dopamine in the brain, a crucial neurotransmitter for controlling movement.
  • Carbidopa: Prevents the breakdown of levodopa, allowing more of it to enter the brain.
  • Entacapone: Prolongs the effect of levodopa by maintaining its level in the blood.

Together, these ingredients provide greater relief from Parkinson's disease symptoms.

✔️ Common side effects include:
  • Uncontrolled movements
  • Nausea and vomiting
  • Reddish-brown discolored urine
  • Diarrhea
  • Muscle pain and cramps
  • Dizziness, drowsiness, and tiredness
  • Abdominal pain and discomfort, heartburn, dry mouth, constipation
  • Mental confusion, hallucinations, and anxiety
  • Chest pain, irregular heart rate
  • Increased sweating and skin rashes
  • Blurred vision
  • Weight loss
  • Headache and joint pain
✔️ Method of Administration:
  • Take each tablet orally with or without food.
  • Each tablet contains one treatment dose and should be administered whole.
✔️ Indication of Stalevo 125mg+31.25mg+200mg Tablet

Treatment of adult patients with Parkinson's disease experiencing end-of-dose motor fluctuations not stabilized on levodopa/DDC inhibitor treatment.

✔️ Pharmacology
  • Levodopa: Converted to dopamine in the brain to alleviate Parkinson's symptoms.
  • Carbidopa: Inhibits peripheral metabolism of levodopa, increasing its availability to the brain.
  • Entacapone: Inhibits catechol-O-methyltransferase (COMT), enhancing and prolonging the effect of levodopa.
✔️ Dosage & Administration of Stalevo 125mg+31.25mg+200mg Tablet

Adults:

  • The optimum daily dose must be determined by careful titration of levodopa in each patient.
  • Patients should take only 1 tablet per dose administration.
  • The maximum recommended daily dose of entacapone is 2,000 mg.
  • This tablet is intended for patients currently treated with corresponding doses of standard-release levodopa/DDC inhibitor and entacapone.

Transferring Patients to Stalevo:

From Levodopa/DDC Inhibitor (Carbidopa or Benserazide) and Entacapone:

  • Direct Transfer: Patients taking standard-release levodopa/carbidopa and entacapone can switch directly to corresponding Stalevo doses.
  • Example: A patient taking 100 mg/25 mg levodopa/carbidopa and 200 mg entacapone four times daily can switch to Stalevo four times daily.
  • Dosing Titration: Adjust Tridopa dosing carefully for optimal response, matching as closely as possible to the total daily levodopa dose.

From Levodopa/Benserazide and Entacapone:

  • Discontinue levodopa/benserazide the night before starting Stalevo the next morning.
  • Start with a dose that provides the same or slightly more levodopa (5-10%).

For Patients Not Currently Treated with Entacapone:

  • Introduction: Consider initiating Stalevo at corresponding doses for patients with Parkinson's disease and end-of-dose motor fluctuations not stabilized on current standard release levodopa/DDC inhibitor treatment.
  • Patients with Dyskinesia or High Levodopa Dose (>800 mg): Introduce entacapone separately and adjust the levodopa dose before switching to Stalevo.
  • Dose Reduction: Reduce levodopa dose by 10-30% within the first days to weeks after starting Stalevo, particularly for patients with dyskinesia.

Dose Adjustment During Treatment:

  • Increasing Levodopa: Increase the frequency of doses and/or use an alternative strength of Stalevo within recommended dose limits.
  • Decreasing Levodopa: Reduce the total daily dose by decreasing the frequency or strength of Stalevo.
  • Concomitant Use of Other Levodopa Products: Follow maximum dose recommendations for combined use with Stalevo.

Discontinuation of Stalevo:

  • When discontinuing Stalevo and switching to levodopa/DDC inhibitor therapy without entacapone, adjust other antiparkinsonian treatments, especially levodopa, to maintain control of parkinsonian symptoms.
✔️ Interaction
  • Drug-Drug Interactions: Inform your doctor if you are taking medications for depression, respiratory diseases, severe allergic reactions, heart diseases, high blood pressure, mental disorders, nausea, convulsions, muscle relaxation, or iron supplements.
  • Drug-Food Interaction: Avoid taking with or shortly after eating protein-rich foods as it may decrease the absorption of the medicine.
✔️ Contraindications

Severe hepatic impairment, narrow-angle glaucoma, pheochromocytoma, MAO inhibitors, history of NMS, or hypersensitivity to components.

✔️ Pregnancy & Lactation
  • Pregnancy: Category C; use only if the benefit justifies the risk.
  • Lactation: Not recommended.
✔️ Precautions & Warnings
  • Pregnancy: Not recommended unless necessary. Consult your doctor.
  • Breastfeeding: Not recommended as it may pass through breast milk. Consult your doctor.
  • Driving: Avoid driving or operating machines if you feel light-headed, dizzy, or drowsy.
  • Kidney: Use with caution in patients with kidney diseases. Consult your doctor.
  • Liver: Not recommended for severe liver disease. Use with caution for other liver problems. Consult your doctor.
  • Allergy: Do not take if allergic to Levodopa, Carbidopa, or Entacapone.
  • Lungs: Use with caution in patients with asthma or other lung diseases. Consult your doctor.
  • Heart Disease: Use with caution if you have had a heart attack or other heart conditions. Consult your doctor.
✔️ Storage Conditions:

Store in a cool and dry place away from sunlight

Frequently Asked Questions (FAQ)

If you or someone else accidentally takes too much ENTACOM PLUS 50MG TABLET, seek immediate medical attention. Symptoms of overdose may include mental confusion, agitation, changes in heart rate, and discoloration of the skin, tongue, eyes, or urine.

Nausea/Vomiting: Take the tablet with food or after meals. Avoid oily or spicy foods. Heartburn: Eat smaller, more frequent meals and avoid rushing while eating. Constipation: Eat high-fiber foods and drink plenty of water. Exercise regularly. Diarrhea: Stay hydrated with fluids like water or fruit juice. Stomach pain: Eat and drink slowly in smaller portions, and use a heating pad on your stomach. Headache: Rest, apply pain balm, and drink hot water or ginger tea. Dizziness: Sit or lie down slowly and drink plenty of water. Avoid coffee and carbonated drinks.

A: Take Stalevo Tablet as advised by your physician. Swallow the tablet with a glass of water, without crushing or chewing it. The correct dose and duration will be decided by your doctor based on your age, body weight, and disease condition. Do not stop taking ENTACOM PLUS 50MG TABLET without consulting your doctor.
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Check our pricing section for Stalevo (125mg+31.25mg+200mg) Tablet 30Pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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